import pandas as pd a = [[1.435415415135154] *10000]*1000 %time a[10][20] df = pd.DataFrame(a) %time df.iat[10,20] CPU times: user 7 µs, sys: 1e+03 ns, total: 8 µs Wall time: 34.1 µs CPU times: user 698 µs, sys: 479 µs, total: 1.18 ms Wall…